Drug interactions
Butalbital + Nabilone
Severity: Moderate
Butalbital and Nabilone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butalbital is a barbiturate and, with nabilone, may produce additive drowsiness, dizziness and impaired judgement. Higher doses or other depressants raise the risk of respiratory depression.
What this interaction means in plain words
Butalbital and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive central nervous system depression.
What to do
Counsel on sedation and avoidance of alcohol and driving; use the lowest effective doses and monitor for excessive drowsiness.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nabilone
Frequently asked questions
Can I take Butalbital with Nabilone?
MediHelp rates the interaction as moderate. Butalbital and Nabilone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Butalbital is a barbiturate and, with nabilone, may produce additive drowsiness, dizziness and impaired judgement. Higher doses or other depressants raise the risk of respiratory depression.
How serious is the interaction between Butalbital and Nabilone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on sedation and avoidance of alcohol and driving; use the lowest effective doses and monitor for excessive drowsiness.
What other medicines interact with Nabilone?
MediHelp also lists interactions of Nabilone with, for example, Alfentanil, Amobarbital, Belladonna and opium. The full list is on the Nabilone page.
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