Drug interactions
Cabazitaxel + Measles mumps and rubella vaccine
Severity: Major
Cabazitaxel and Measles mumps and rubella vaccine: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cabazitaxel is a cytotoxic taxane causing myelosuppression and immunosuppression. Live vaccines may cause disseminated vaccine-virus infection and respond poorly.
What this interaction means in plain words
Cabazitaxel and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cabazitaxel belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.
Why it happens
Chemotherapy-induced immunosuppression allows uncontrolled replication of live vaccine virus.
What to do
Avoid live vaccines during chemotherapy and until immune recovery per guidelines. Use inactivated alternatives where possible.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Other interactions of Cabazitaxel
Frequently asked questions
Can I take Cabazitaxel with Measles mumps and rubella vaccine?
MediHelp rates the interaction as major. Cabazitaxel and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cabazitaxel is a cytotoxic taxane causing myelosuppression and immunosuppression. Live vaccines may cause disseminated vaccine-virus infection and respond poorly.
How serious is the interaction between Cabazitaxel and Measles mumps and rubella vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and until immune recovery per guidelines. Use inactivated alternatives where possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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