Drug interactions
Cabergoline + Iloperidone
Severity: Moderate
Cabergoline and Iloperidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone is an atypical antipsychotic with dopamine D2 antagonism, which opposes the effects of the dopamine agonist cabergoline. The result may be reduced prolactin lowering or loss of symptom control. Combined use is generally counterproductive.
What this interaction means in plain words
Cabergoline and Iloperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabergoline belongs to Endocrine; Iloperidone belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism at dopamine D2 receptors.
What to do
Avoid the combination where possible, and monitor prolactin levels and clinical response if both drugs must be used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cabergoline
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Cabergoline with Iloperidone?
MediHelp rates the interaction as moderate. Cabergoline and Iloperidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iloperidone is an atypical antipsychotic with dopamine D2 antagonism, which opposes the effects of the dopamine agonist cabergoline. The result may be reduced prolactin lowering or loss of symptom control. Combined use is generally counterproductive.
How serious is the interaction between Cabergoline and Iloperidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, and monitor prolactin levels and clinical response if both drugs must be used.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Benperidol, Chlorpromazine, Clarithromycin. The full list is on the Cabergoline page.
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