Drug interactions
Cabergoline + Lurasidone
Severity: Moderate
Cabergoline and Lurasidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lurasidone blocks D2 receptors and can oppose cabergoline's dopaminergic effect, reducing control of hyperprolactinemia or Parkinson symptoms. Both drugs may also lower blood pressure.
What this interaction means in plain words
Cabergoline and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabergoline belongs to Endocrine; Lurasidone belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism at D2 receptors, with additive hypotensive effects.
What to do
Monitor prolactin levels or parkinsonian symptoms and blood pressure. Review whether both agents are necessary and adjust doses accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Other interactions of Cabergoline
Frequently asked questions
Can I take Cabergoline with Lurasidone?
MediHelp rates the interaction as moderate. Cabergoline and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lurasidone blocks D2 receptors and can oppose cabergoline's dopaminergic effect, reducing control of hyperprolactinemia or Parkinson symptoms. Both drugs may also lower blood pressure.
How serious is the interaction between Cabergoline and Lurasidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor prolactin levels or parkinsonian symptoms and blood pressure. Review whether both agents are necessary and adjust doses accordingly.
What other medicines interact with Lurasidone?
MediHelp also lists interactions of Lurasidone with, for example, Apalutamide, Atazanavir, Carbamazepine. The full list is on the Lurasidone page.
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