Drug interactions
Cabergoline + Phentermine
Severity: Moderate
Cabergoline and Phentermine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a sympathomimetic that can raise blood pressure and heart rate. Cabergoline may add vasoconstrictive effects, so hypertension could be more pronounced. Cabergoline-associated valvulopathy also matters in an anorectic setting, where valve effects are a known concern.
What this interaction means in plain words
Cabergoline and Phentermine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cabergoline belongs to Endocrine; Phentermine belongs to Central Nervous System.
Why it happens
Additive pressor effects from sympathomimetic and ergoline vasoconstrictive actions.
What to do
Monitor blood pressure and heart rate, and avoid in patients with uncontrolled hypertension or known valvular disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cabergoline
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Cabergoline with Phentermine?
MediHelp rates the interaction as moderate. Cabergoline and Phentermine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phentermine is a sympathomimetic that can raise blood pressure and heart rate. Cabergoline may add vasoconstrictive effects, so hypertension could be more pronounced. Cabergoline-associated valvulopathy also matters in an anorectic setting, where valve effects are a known concern.
How serious is the interaction between Cabergoline and Phentermine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and avoid in patients with uncontrolled hypertension or known valvular disease.
What other medicines interact with Cabergoline?
MediHelp also lists interactions of Cabergoline with, for example, Benperidol, Chlorpromazine, Clarithromycin. The full list is on the Cabergoline page.
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