Drug interactions
Calcium + Deflazacort
Severity: Minor
Calcium and Deflazacort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucocorticoids such as deflazacort reduce intestinal calcium absorption and increase urinary calcium loss, contributing to bone loss with long-term use. Calcium supplements are often given deliberately to offset this. The effect on serum calcium is generally modest.
What this interaction means in plain words
Calcium and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium belongs to Gastrointestinal Tract; Deflazacort belongs to Miscellaneous.
Why it happens
Glucocorticoids decrease intestinal calcium absorption and increase renal calcium excretion.
What to do
Ensure adequate calcium and vitamin D intake during prolonged therapy and assess bone density in long-term users.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Calcium with Deflazacort?
MediHelp rates the interaction as minor. Calcium and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucocorticoids such as deflazacort reduce intestinal calcium absorption and increase urinary calcium loss, contributing to bone loss with long-term use. Calcium supplements are often given deliberately to offset this. The effect on serum calcium is generally modest.
How serious is the interaction between Calcium and Deflazacort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure adequate calcium and vitamin D intake during prolonged therapy and assess bone density in long-term users.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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