Drug interactions
Calcium + Tiludronate
Severity: Moderate
Calcium and Tiludronate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium reduces tiludronate absorption, which may lessen its therapeutic effect.
What this interaction means in plain words
Calcium and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Tiludronate belongs to Musculoskeletal.
Why it happens
Calcium chelates tiludronate in the gastrointestinal tract, inhibiting absorption.
What to do
Take tiludronate at least 2 hours before or after calcium-containing products.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Calcium
- Calcium + Ceftriaxone Contraindicated
- Acalabrutinib + Calcium Moderate
- Alendronate + Calcium Moderate
- Atazanavir + Calcium Moderate
- Baloxavir marboxil + Calcium Moderate
- Bendroflumethiazide + Calcium Moderate
Other interactions of Tiludronate
- Acetylsalicylic acid + Tiludronate Moderate
- Aluminum hydroxide + Tiludronate Moderate
- Calcium acetate + Tiludronate Moderate
- Calcium carbonate + Tiludronate Moderate
- Calcium chloride + Tiludronate Moderate
- Calcium citrate + Tiludronate Moderate
Frequently asked questions
Can I take Calcium with Tiludronate?
MediHelp rates the interaction as moderate. Calcium and Tiludronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium reduces tiludronate absorption, which may lessen its therapeutic effect.
How serious is the interaction between Calcium and Tiludronate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take tiludronate at least 2 hours before or after calcium-containing products.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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