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Drug interactions

Calcium carbonate + Celiprolol

Severity: Moderate

Calcium carbonate and Celiprolol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral calcium salts and antacids may lower celiprolol absorption, reducing its blood pressure and heart rate effects. The clinical effect is generally modest but may reduce control of hypertension or angina.

What this interaction means in plain words

Calcium carbonate and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Calcium carbonate may bind celiprolol or alter gastric conditions in the gut, reducing its absorption.

What to do

Separate doses by at least 2 hours, giving celiprolol first. Monitor blood pressure and heart rate if the antacid is used regularly.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Calcium carbonate with Celiprolol?

MediHelp rates the interaction as moderate. Calcium carbonate and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium salts and antacids may lower celiprolol absorption, reducing its blood pressure and heart rate effects. The clinical effect is generally modest but may reduce control of hypertension or angina.

How serious is the interaction between Calcium carbonate and Celiprolol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate doses by at least 2 hours, giving celiprolol first. Monitor blood pressure and heart rate if the antacid is used regularly.

What other medicines interact with Calcium carbonate?

MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.

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