Drug interactions
Calcium carbonate + Gabapentin
Severity: Minor
Calcium carbonate and Gabapentin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antacids reduce the oral bioavailability of gabapentin by a modest amount. This may slightly weaken seizure or pain control.
What this interaction means in plain words
Calcium carbonate and Gabapentin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium carbonate belongs to Gastrointestinal Tract; Gabapentin belongs to Central Nervous System.
Why it happens
Antacid cations reduce gabapentin absorption, probably by binding or altering gut conditions.
What to do
Take gabapentin at least 2 hours after the calcium antacid.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Calcium carbonate and Gabapentin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Calcium carbonate
Other interactions of Gabapentin
Frequently asked questions
Can I take Calcium carbonate with Gabapentin?
MediHelp rates the interaction as minor. Calcium carbonate and Gabapentin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antacids reduce the oral bioavailability of gabapentin by a modest amount. This may slightly weaken seizure or pain control.
How serious is the interaction between Calcium carbonate and Gabapentin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take gabapentin at least 2 hours after the calcium antacid.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
