Drug interactions
Calcium carbonate + Neomycin po
Severity: Minor
Calcium carbonate and Neomycin po: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral neomycin can damage the intestinal mucosa and bind to divalent cations, which may reduce the absorption of calcium from the gut. The effect on calcium status is generally small and is rarely clinically important.
What this interaction means in plain words
Calcium carbonate and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Neomycin may impair intestinal absorption of calcium through mucosal effects and complexation, though the mechanism is not firmly established.
What to do
No routine action needed; monitor serum calcium only in patients on prolonged neomycin therapy who depend on calcium supplementation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Frequently asked questions
Can I take Calcium carbonate with Neomycin po?
MediHelp rates the interaction as minor. Calcium carbonate and Neomycin po have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral neomycin can damage the intestinal mucosa and bind to divalent cations, which may reduce the absorption of calcium from the gut. The effect on calcium status is generally small and is rarely clinically important.
How serious is the interaction between Calcium carbonate and Neomycin po?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action needed; monitor serum calcium only in patients on prolonged neomycin therapy who depend on calcium supplementation.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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