Drug interactions
Calcium carbonate + Quinapril
Severity: Minor
Calcium carbonate and Quinapril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinapril tablets contain magnesium carbonate as an excipient to buffer tetrazole formation, and antacids have been reported to reduce ACE inhibitor absorption slightly. Any loss of blood pressure control is expected to be small.
What this interaction means in plain words
Calcium carbonate and Quinapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Antacids may modestly reduce oral absorption of the ACE inhibitor; the mechanism is not firmly established.
What to do
Separate administration by about 2 hours if practical and check blood pressure if antacid use is regular.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Calcium carbonate
Frequently asked questions
Can I take Calcium carbonate with Quinapril?
MediHelp rates the interaction as minor. Calcium carbonate and Quinapril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinapril tablets contain magnesium carbonate as an excipient to buffer tetrazole formation, and antacids have been reported to reduce ACE inhibitor absorption slightly. Any loss of blood pressure control is expected to be small.
How serious is the interaction between Calcium carbonate and Quinapril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by about 2 hours if practical and check blood pressure if antacid use is regular.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
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