Drug interactions
Calcium gluconate + Ferrous fumarate
Severity: Minor
Calcium gluconate and Ferrous fumarate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral calcium gluconate may reduce absorption of oral iron when both are taken together. Clinical impact is generally small but can slow iron repletion.
What this interaction means in plain words
Calcium gluconate and Ferrous fumarate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Calcium gluconate belongs to Gastrointestinal Tract; Ferrous fumarate belongs to Miscellaneous.
Why it happens
Calcium competes with iron for intestinal absorption.
What to do
Take oral iron at least 2 hours apart from calcium gluconate. Monitor hemoglobin and ferritin in prolonged co-therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ferrous fumarate
Other interactions of Calcium gluconate
- Calcium gluconate + Ceftriaxone Contraindicated
- Calcium gluconate + Digoxin Major
- Alendronate + Calcium gluconate Moderate
- Amlodipine-atorvastatin + Calcium gluconate Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Calcium gluconate Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Calcium gluconate Moderate
Frequently asked questions
Can I take Calcium gluconate with Ferrous fumarate?
MediHelp rates the interaction as minor. Calcium gluconate and Ferrous fumarate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral calcium gluconate may reduce absorption of oral iron when both are taken together. Clinical impact is generally small but can slow iron repletion.
How serious is the interaction between Calcium gluconate and Ferrous fumarate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oral iron at least 2 hours apart from calcium gluconate. Monitor hemoglobin and ferritin in prolonged co-therapy.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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