Drug interactions
Canagliflozin-metformin + Felodipine
Severity: Minor
Canagliflozin-metformin and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dihydropyridine calcium channel blockers may slightly impair glucose tolerance, but clinically meaningful loss of glycemic control is uncommon.
What this interaction means in plain words
Canagliflozin-metformin and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Canagliflozin-metformin belongs to Endocrine; Felodipine belongs to Cardiovascular.
Why it happens
Calcium channel blockade may modestly reduce insulin secretion and sensitivity.
What to do
Check blood glucose when felodipine is started or stopped and adjust antidiabetic doses only if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Canagliflozin-metformin
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Canagliflozin-metformin with Felodipine?
MediHelp rates the interaction as minor. Canagliflozin-metformin and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dihydropyridine calcium channel blockers may slightly impair glucose tolerance, but clinically meaningful loss of glycemic control is uncommon.
How serious is the interaction between Canagliflozin-metformin and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose when felodipine is started or stopped and adjust antidiabetic doses only if needed.
What other medicines interact with Canagliflozin-metformin?
MediHelp also lists interactions of Canagliflozin-metformin with, for example, Contrast media, Diatrizoate, Diatrizoate meglumine / diatrizoate. The full list is on the Canagliflozin-metformin page.
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