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Drug interactions

Candesartan-hydrochlorothiazide + Cefadroxil

Severity: Minor

Candesartan-hydrochlorothiazide and Cefadroxil: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cefadroxil and hydrochlorothiazide are both renally secreted and might compete for tubular transport. Any rise in drug levels is small and rarely clinically meaningful.

What this interaction means in plain words

Candesartan-hydrochlorothiazide and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Candesartan-hydrochlorothiazide belongs to Cardiovascular; Cefadroxil belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Possible competition for renal tubular organic anion secretion.

What to do

No change is usually needed. Adjust cefadroxil dose in patients with reduced renal function.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Candesartan-hydrochlorothiazide with Cefadroxil?

MediHelp rates the interaction as minor. Candesartan-hydrochlorothiazide and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefadroxil and hydrochlorothiazide are both renally secreted and might compete for tubular transport. Any rise in drug levels is small and rarely clinically meaningful.

How serious is the interaction between Candesartan-hydrochlorothiazide and Cefadroxil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change is usually needed. Adjust cefadroxil dose in patients with reduced renal function.

What other medicines interact with Candesartan-hydrochlorothiazide?

MediHelp also lists interactions of Candesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Candesartan-hydrochlorothiazide page.

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