Drug interactions
Capecitabine + Fostemsavir
Severity: Minor
Capecitabine and Fostemsavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fostemsavir at supratherapeutic doses prolongs the QT interval, and capecitabine may contribute slightly to cardiac risk. At recommended doses the combined effect is probably small.
What this interaction means in plain words
Capecitabine and Fostemsavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Capecitabine belongs to Oncology; Fostemsavir belongs to Anti Virals.
Why it happens
Fostemsavir's active metabolite delays cardiac repolarization at high exposures; capecitabine contribution is uncertain.
What to do
Use recommended fostemsavir doses and check ECG if the patient has other QT risk factors or electrolyte disturbances.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Capecitabine
Other interactions of Fostemsavir
- Apalutamide + Fostemsavir Contraindicated
- Carbamazepine + Fostemsavir Contraindicated
- Enzalutamide + Fostemsavir Contraindicated
- Fostemsavir + Mitotane Contraindicated
- Fostemsavir + Phenytoin Contraindicated
- Fostemsavir + Rifampicin Contraindicated
Frequently asked questions
Can I take Capecitabine with Fostemsavir?
MediHelp rates the interaction as minor. Capecitabine and Fostemsavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fostemsavir at supratherapeutic doses prolongs the QT interval, and capecitabine may contribute slightly to cardiac risk. At recommended doses the combined effect is probably small.
How serious is the interaction between Capecitabine and Fostemsavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use recommended fostemsavir doses and check ECG if the patient has other QT risk factors or electrolyte disturbances.
What other medicines interact with Capecitabine?
MediHelp also lists interactions of Capecitabine with, for example, Adenovirus types 4 and 7 live, Arsenic trioxide, Axicabtagene ciloleucel. The full list is on the Capecitabine page.
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