Drug interactions
Caplacizumab + Cilostazol
Severity: Moderate
Caplacizumab and Cilostazol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs impair platelet function, so their combined use may increase bleeding risk.
What this interaction means in plain words
Caplacizumab and Cilostazol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Caplacizumab belongs to Cardiovascular; Cilostazol belongs to Cardiovascular.
Why it happens
Additive effects on platelet function through vWF-platelet binding blockade and PDE3 inhibition.
What to do
Monitor for bleeding and consider holding cilostazol if bleeding occurs during caplacizumab therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Caplacizumab and Cilostazol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cilostazol
Other interactions of Caplacizumab
Frequently asked questions
Can I take Caplacizumab with Cilostazol?
MediHelp rates the interaction as moderate. Caplacizumab and Cilostazol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs impair platelet function, so their combined use may increase bleeding risk.
How serious is the interaction between Caplacizumab and Cilostazol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and consider holding cilostazol if bleeding occurs during caplacizumab therapy.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Anagrelide, Betrixaban. The full list is on the Cilostazol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
