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Drug interactions

Capreomycin + Cidofovir

Severity: Contraindicated

Capreomycin and Cidofovir: contraindicated interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both drugs are nephrotoxic, and capreomycin can also cause ototoxicity and electrolyte loss. Using them together raises the risk of acute kidney injury.

What this interaction means in plain words

Capreomycin and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Evidence level: Moderate

Why it happens

Additive nephrotoxicity.

What to do

Do not use together, and follow the cidofovir labeling to avoid nephrotoxic drugs. Choose an alternative antimycobacterial or antiviral agent.

What to ask your pharmacist

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Capreomycin with Cidofovir?

MediHelp rates the interaction as contraindicated. Capreomycin and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs are nephrotoxic, and capreomycin can also cause ototoxicity and electrolyte loss. Using them together raises the risk of acute kidney injury.

How serious is the interaction between Capreomycin and Cidofovir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together, and follow the cidofovir labeling to avoid nephrotoxic drugs. Choose an alternative antimycobacterial or antiviral agent.

What other medicines interact with Cidofovir?

MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.

Full monographs, dosing and an interaction checker in the MediHelp app

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