Drug interactions
Cephaloridine + Cidofovir
Severity: Contraindicated
Cephaloridine and Cidofovir: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cephaloridine is a nephrotoxic cephalosporin that is no longer in general use. With cidofovir it would add to proximal tubular injury and the risk of renal failure.
What this interaction means in plain words
Cephaloridine and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
Additive nephrotoxicity to the proximal tubule.
What to do
Avoid the combination and use a non-nephrotoxic antibiotic. Cidofovir labeling prohibits concurrent nephrotoxic agents.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Cidofovir
- Amikacin + Cidofovir Contraindicated
- Amphotericin b deoxycholate + Cidofovir Contraindicated
- Amphotericin b + Cidofovir Contraindicated
- Bacitracin + Cidofovir Contraindicated
- Capreomycin + Cidofovir Contraindicated
- Cidofovir + Cisplatin Contraindicated
Frequently asked questions
Can I take Cephaloridine with Cidofovir?
MediHelp rates the interaction as contraindicated. Cephaloridine and Cidofovir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Cephaloridine is a nephrotoxic cephalosporin that is no longer in general use. With cidofovir it would add to proximal tubular injury and the risk of renal failure.
How serious is the interaction between Cephaloridine and Cidofovir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-nephrotoxic antibiotic. Cidofovir labeling prohibits concurrent nephrotoxic agents.
What other medicines interact with Cidofovir?
MediHelp also lists interactions of Cidofovir with, for example, Amikacin, Amphotericin b deoxycholate, Amphotericin b. The full list is on the Cidofovir page.
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