Drug interactions
Capreomycin + Oxaliplatin
Severity: Moderate
Capreomycin and Oxaliplatin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Capreomycin is nephrotoxic and ototoxic, and oxaliplatin can affect renal function and cause neurotoxicity. Combined use may increase kidney injury and hearing or neural toxicity.
What this interaction means in plain words
Capreomycin and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive nephrotoxicity and ototoxicity.
What to do
Monitor serum creatinine, electrolytes and hearing during combined therapy. Consider alternative antimycobacterial agents if renal function declines.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Frequently asked questions
Can I take Capreomycin with Oxaliplatin?
MediHelp rates the interaction as moderate. Capreomycin and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Capreomycin is nephrotoxic and ototoxic, and oxaliplatin can affect renal function and cause neurotoxicity. Combined use may increase kidney injury and hearing or neural toxicity.
How serious is the interaction between Capreomycin and Oxaliplatin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine, electrolytes and hearing during combined therapy. Consider alternative antimycobacterial agents if renal function declines.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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