Drug interactions
Captopril + Dinutuximab
Severity: Moderate
Captopril and Dinutuximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dinutuximab commonly causes infusion-related hypotension and capillary leak, and captopril lowers blood pressure. Taken together they may increase the risk or severity of hypotension during infusions.
What this interaction means in plain words
Captopril and Dinutuximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Captopril belongs to Cardiovascular; Dinutuximab belongs to Oncology.
Why it happens
Additive hypotensive effects through pharmacodynamic synergism.
What to do
Monitor blood pressure closely during and after dinutuximab infusions, and consider holding captopril on infusion days if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Captopril
- Aliskiren + Captopril Contraindicated
- Captopril + Sacubitril / valsartan Contraindicated
- Captopril + Sacubitril-valsartan Contraindicated
- Amifostine + Captopril Major
- Amiloride + Captopril Major
- Amlodipine-hydrochlorothiazide-valsartan + Captopril Major
Other interactions of Dinutuximab
- Amlodipine-benazepril + Dinutuximab Moderate
- Benazepril + Dinutuximab Moderate
- Captopril-hydrochlorothiazide + Dinutuximab Moderate
- Dinutuximab + Lomustine Moderate
- Dinutuximab + Oxaliplatin Moderate
- Dinutuximab + Siponimod Minor
Frequently asked questions
Can I take Captopril with Dinutuximab?
MediHelp rates the interaction as moderate. Captopril and Dinutuximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dinutuximab commonly causes infusion-related hypotension and capillary leak, and captopril lowers blood pressure. Taken together they may increase the risk or severity of hypotension during infusions.
How serious is the interaction between Captopril and Dinutuximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely during and after dinutuximab infusions, and consider holding captopril on infusion days if hypotension develops.
What other medicines interact with Captopril?
MediHelp also lists interactions of Captopril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Captopril page.
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