Drug interactions
Benazepril + Dinutuximab
Severity: Moderate
Benazepril and Dinutuximab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dinutuximab commonly causes infusion reactions with hypotension and capillary leak. Concurrent benazepril may worsen hypotension during infusion.
What this interaction means in plain words
Benazepril and Dinutuximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Dinutuximab belongs to Oncology.
Why it happens
Additive hypotensive effects from antibody-related capillary leak and ACE inhibition.
What to do
Monitor blood pressure closely during infusions and consider withholding benazepril on infusion days if hypotension is a concern.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Benazepril
- Aliskiren + Benazepril Contraindicated
- Benazepril + Sacubitril / valsartan Contraindicated
- Benazepril + Sacubitril-valsartan Contraindicated
- Amifostine + Benazepril Major
- Amiloride + Benazepril Major
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Major
Other interactions of Dinutuximab
- Amlodipine-benazepril + Dinutuximab Moderate
- Captopril-hydrochlorothiazide + Dinutuximab Moderate
- Captopril + Dinutuximab Moderate
- Dinutuximab + Lomustine Moderate
- Dinutuximab + Oxaliplatin Moderate
- Dinutuximab + Siponimod Minor
Frequently asked questions
Can I take Benazepril with Dinutuximab?
MediHelp rates the interaction as moderate. Benazepril and Dinutuximab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dinutuximab commonly causes infusion reactions with hypotension and capillary leak. Concurrent benazepril may worsen hypotension during infusion.
How serious is the interaction between Benazepril and Dinutuximab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely during infusions and consider withholding benazepril on infusion days if hypotension is a concern.
What other medicines interact with Benazepril?
MediHelp also lists interactions of Benazepril with, for example, Aliskiren, Sacubitril / valsartan, Sacubitril-valsartan. The full list is on the Benazepril page.
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