Drug interactions
Carbamazepine + Deferasirox
Severity: Moderate
Carbamazepine and Deferasirox: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Deferasirox may alter carbamazepine exposure, and carbamazepine as an inducer may lower deferasirox exposure and iron-chelating effect.
What this interaction means in plain words
Carbamazepine and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbamazepine belongs to Central Nervous System; Deferasirox belongs to Miscellaneous.
Why it happens
Deferasirox affects CYP3A4 and CYP2C8 and carbamazepine induces UGT, so exposure of each drug may change.
What to do
Monitor carbamazepine levels and serum ferritin, and adjust doses as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carbamazepine
- Artemether / lumefantrine + Carbamazepine Contraindicated
- Cabotegravir + Carbamazepine Contraindicated
- Carbamazepine + Delamanid Contraindicated
- Carbamazepine + Dienogest / estradiol valerate Contraindicated
- Carbamazepine + Doravirine Contraindicated
- Carbamazepine + Elbasvir / grazoprevir Contraindicated
Other interactions of Deferasirox
Frequently asked questions
Can I take Carbamazepine with Deferasirox?
MediHelp rates the interaction as moderate. Carbamazepine and Deferasirox can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deferasirox may alter carbamazepine exposure, and carbamazepine as an inducer may lower deferasirox exposure and iron-chelating effect.
How serious is the interaction between Carbamazepine and Deferasirox?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor carbamazepine levels and serum ferritin, and adjust doses as needed.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
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