Drug interactions
Carbonyl iron + Famotidine
Severity: Moderate
Carbonyl iron and Famotidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Reduced gastric acidity impairs conversion of oral iron to its absorbable ferrous form, lowering iron absorption. With prolonged use this may blunt the response to iron therapy.
What this interaction means in plain words
Carbonyl iron and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Famotidine belongs to Gastrointestinal Tract.
Why it happens
Famotidine raises gastric pH, decreasing dissolution and absorption of oral iron.
What to do
Monitor hemoglobin and ferritin in patients on long-term combined therapy. Consider taking iron with vitamin C or reassessing the need for acid suppression.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Famotidine
Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Frequently asked questions
Can I take Carbonyl iron with Famotidine?
MediHelp rates the interaction as moderate. Carbonyl iron and Famotidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Reduced gastric acidity impairs conversion of oral iron to its absorbable ferrous form, lowering iron absorption. With prolonged use this may blunt the response to iron therapy.
How serious is the interaction between Carbonyl iron and Famotidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor hemoglobin and ferritin in patients on long-term combined therapy. Consider taking iron with vitamin C or reassessing the need for acid suppression.
What other medicines interact with Famotidine?
MediHelp also lists interactions of Famotidine with, for example, Atazanavir, Dasatinib, Infigratinib. The full list is on the Famotidine page.
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