Drug interactions
Carbonyl iron + Sarecycline
Severity: Moderate
Carbonyl iron and Sarecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron may bind sarecycline in the gut and lower its absorption. This could modestly weaken acne treatment response.
What this interaction means in plain words
Carbonyl iron and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Sarecycline belongs to Anti Bacterial.
Why it happens
Chelation of sarecycline by iron cations in the gastrointestinal tract.
What to do
Separate sarecycline and iron by at least 2 to 3 hours, taking sarecycline first. Reassess acne response if separation is not possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Carbonyl iron with Sarecycline?
MediHelp rates the interaction as moderate. Carbonyl iron and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron may bind sarecycline in the gut and lower its absorption. This could modestly weaken acne treatment response.
How serious is the interaction between Carbonyl iron and Sarecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline and iron by at least 2 to 3 hours, taking sarecycline first. Reassess acne response if separation is not possible.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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