Drug interactions
Carbonyl iron + Vitamin e
Severity: Minor
Carbonyl iron and Vitamin e: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose vitamin E has been reported to blunt the haematological response to iron in some settings, and iron may in turn promote oxidation of vitamin E. The clinical relevance at usual supplement doses is small.
What this interaction means in plain words
Carbonyl iron and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbonyl iron belongs to Miscellaneous; Vitamin e belongs to Gastrointestinal Tract.
Why it happens
Mechanism is not firmly established; possible reduced iron absorption or redox interaction in the gut.
What to do
No routine action is needed. Monitor haemoglobin and ferritin if high-dose vitamin E is used long term in a patient treated for iron deficiency.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Other interactions of Vitamin e
- Betrixaban + Vitamin e Moderate
- Phenindione + Vitamin e Moderate
- Selumetinib + Vitamin e Moderate
- Vitamin e + Warfarin Moderate
- Alfalfa + Vitamin e Minor
- Antithrombin alfa + Vitamin e Minor
Frequently asked questions
Can I take Carbonyl iron with Vitamin e?
MediHelp rates the interaction as minor. Carbonyl iron and Vitamin e have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose vitamin E has been reported to blunt the haematological response to iron in some settings, and iron may in turn promote oxidation of vitamin E. The clinical relevance at usual supplement doses is small.
How serious is the interaction between Carbonyl iron and Vitamin e?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Monitor haemoglobin and ferritin if high-dose vitamin E is used long term in a patient treated for iron deficiency.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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