Drug interactions
Cariprazine + Cyproheptadine
Severity: Minor
Cariprazine and Cyproheptadine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can cause somnolence, so combined use may increase drowsiness and impair alertness.
What this interaction means in plain words
Cariprazine and Cyproheptadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cariprazine belongs to Central Nervous System; Cyproheptadine belongs to Respiratory.
Why it happens
Additive CNS depression from H1 antagonism and antipsychotic receptor blockade.
What to do
Counsel on drowsiness and driving, and lower the dose of cyproheptadine if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cariprazine and Cyproheptadine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cyproheptadine
- Cyproheptadine + Isocarboxazid Contraindicated
- Cyproheptadine + Phenelzine Contraindicated
- Cyproheptadine + Tranylcypromine Contraindicated
- Alfentanil + Cyproheptadine Major
- Belladonna and opium + Cyproheptadine Major
- Benzhydrocodone / acetaminophen + Cyproheptadine Major
Other interactions of Cariprazine
Frequently asked questions
Can I take Cariprazine with Cyproheptadine?
MediHelp rates the interaction as minor. Cariprazine and Cyproheptadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs can cause somnolence, so combined use may increase drowsiness and impair alertness.
How serious is the interaction between Cariprazine and Cyproheptadine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on drowsiness and driving, and lower the dose of cyproheptadine if sedation is troublesome.
What other medicines interact with Cyproheptadine?
MediHelp also lists interactions of Cyproheptadine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Cyproheptadine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
