Drug interactions
Cariprazine + Metformin-repaglinide
Severity: Minor
Cariprazine and Metformin-repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cariprazine, as an atypical antipsychotic, may cause hyperglycemia and metabolic changes. This can offset the effect of metformin and repaglinide.
What this interaction means in plain words
Cariprazine and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cariprazine belongs to Central Nervous System; Metformin-repaglinide belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism through antipsychotic-associated glucose dysregulation.
What to do
Check glucose and HbA1c at baseline and periodically during cariprazine therapy, and adjust antidiabetic treatment if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cariprazine and Metformin-repaglinide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Metformin-repaglinide
Other interactions of Cariprazine
Frequently asked questions
Can I take Cariprazine with Metformin-repaglinide?
MediHelp rates the interaction as minor. Cariprazine and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cariprazine, as an atypical antipsychotic, may cause hyperglycemia and metabolic changes. This can offset the effect of metformin and repaglinide.
How serious is the interaction between Cariprazine and Metformin-repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check glucose and HbA1c at baseline and periodically during cariprazine therapy, and adjust antidiabetic treatment if needed.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
