Drug interactions
Carisoprodol + Lurasidone
Severity: Moderate
Carisoprodol and Lurasidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lurasidone can cause somnolence and, together with carisoprodol, may increase drowsiness and impair psychomotor performance. The effect is generally predictable and manageable.
What this interaction means in plain words
Carisoprodol and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carisoprodol belongs to Musculoskeletal; Lurasidone belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects.
What to do
Monitor for sedation and dizziness, particularly after dose changes. Counsel the patient about driving and alcohol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carisoprodol
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Carisoprodol with Lurasidone?
MediHelp rates the interaction as moderate. Carisoprodol and Lurasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lurasidone can cause somnolence and, together with carisoprodol, may increase drowsiness and impair psychomotor performance. The effect is generally predictable and manageable.
How serious is the interaction between Carisoprodol and Lurasidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and dizziness, particularly after dose changes. Counsel the patient about driving and alcohol.
What other medicines interact with Carisoprodol?
MediHelp also lists interactions of Carisoprodol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Carisoprodol page.
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