Drug interactions
Carvedilol + Pomalidomide
Severity: Minor
Carvedilol and Pomalidomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol inhibits P-glycoprotein, and pomalidomide is a P-gp substrate, so exposure may rise modestly. The clinical consequence is likely small.
What this interaction means in plain words
Carvedilol and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carvedilol belongs to Cardiovascular; Pomalidomide belongs to Miscellaneous.
Why it happens
Inhibition of P-glycoprotein efflux, which may modestly increase pomalidomide exposure.
What to do
No dose change is usually needed; monitor for pomalidomide adverse effects such as neutropenia and fatigue.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Carvedilol
Other interactions of Pomalidomide
- Deferiprone + Pomalidomide Major
- Ethinyl estradiol-drospirenone + Pomalidomide Major
- Fluvoxamine + Pomalidomide Major
- Apalutamide + Pomalidomide Moderate
- Brivaracetam + Pomalidomide Moderate
- Carbamazepine + Pomalidomide Moderate
Frequently asked questions
Can I take Carvedilol with Pomalidomide?
MediHelp rates the interaction as minor. Carvedilol and Pomalidomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Carvedilol inhibits P-glycoprotein, and pomalidomide is a P-gp substrate, so exposure may rise modestly. The clinical consequence is likely small.
How serious is the interaction between Carvedilol and Pomalidomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for pomalidomide adverse effects such as neutropenia and fatigue.
What other medicines interact with Carvedilol?
MediHelp also lists interactions of Carvedilol with, for example, Amifostine, Amiodarone, Arformoterol. The full list is on the Carvedilol page.
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