Drug interactions
Cefadroxil + Celecoxib
Severity: Minor
Cefadroxil and Celecoxib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are acidic and eliminated in part by renal tubular secretion, so competition could theoretically raise levels of either. Celecoxib is predominantly cleared by hepatic metabolism, so any effect is likely negligible.
What this interaction means in plain words
Cefadroxil and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefadroxil belongs to Anti Bacterial; Celecoxib belongs to Musculoskeletal.
Why it happens
Theoretical competition for renal tubular anion secretion; not established as significant for celecoxib.
What to do
No action is needed; be aware of this in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Cefadroxil with Celecoxib?
MediHelp rates the interaction as minor. Cefadroxil and Celecoxib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are acidic and eliminated in part by renal tubular secretion, so competition could theoretically raise levels of either. Celecoxib is predominantly cleared by hepatic metabolism, so any effect is likely negligible.
How serious is the interaction between Cefadroxil and Celecoxib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed; be aware of this in patients with renal impairment.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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