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Drug interactions

Cefadroxil + Ketoprofen

Severity: Minor

Cefadroxil and Ketoprofen: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Cefadroxil and ketoprofen are both organic anions secreted by renal tubular transporters. Competition could slightly raise concentrations of either drug, but no clinically important effect is established at usual doses.

What this interaction means in plain words

Cefadroxil and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cefadroxil belongs to Anti Bacterial; Ketoprofen belongs to Musculoskeletal.

Evidence level: Low

Why it happens

Competition for renal tubular secretion through organic anion transporters.

What to do

No specific action is needed in patients with normal renal function. Monitor renal function and for adverse effects if the patient has significant renal impairment.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Cefadroxil with Ketoprofen?

MediHelp rates the interaction as minor. Cefadroxil and Ketoprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefadroxil and ketoprofen are both organic anions secreted by renal tubular transporters. Competition could slightly raise concentrations of either drug, but no clinically important effect is established at usual doses.

How serious is the interaction between Cefadroxil and Ketoprofen?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed in patients with normal renal function. Monitor renal function and for adverse effects if the patient has significant renal impairment.

What other medicines interact with Ketoprofen?

MediHelp also lists interactions of Ketoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Ketoprofen page.

Full monographs, dosing and an interaction checker in the MediHelp app

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