Drug interactions
Cefadroxil + Mesalamine
Severity: Minor
Cefadroxil and Mesalamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefadroxil is cleared by renal tubular secretion and could compete with mesalamine metabolites for it. Any rise in mesalamine exposure is expected to be small.
What this interaction means in plain words
Cefadroxil and Mesalamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefadroxil belongs to Anti Bacterial; Mesalamine belongs to Gastrointestinal Tract.
Why it happens
Competition for renal tubular organic anion secretion.
What to do
No dose change is needed. Monitor renal function in patients with underlying kidney disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Other interactions of Cefadroxil
- Amikacin + Cefadroxil Moderate
- Avelumab + Cefadroxil Moderate
- Balstilimab + Cefadroxil Moderate
- Bcg vaccine live + Cefadroxil Moderate
- Cefadroxil + Cholera vaccine Moderate
- Cefadroxil + Gentamicin Moderate
Frequently asked questions
Can I take Cefadroxil with Mesalamine?
MediHelp rates the interaction as minor. Cefadroxil and Mesalamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefadroxil is cleared by renal tubular secretion and could compete with mesalamine metabolites for it. Any rise in mesalamine exposure is expected to be small.
How serious is the interaction between Cefadroxil and Mesalamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Monitor renal function in patients with underlying kidney disease.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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