Drug interactions
Cefdinir + Willow bark
Severity: Minor
Cefdinir and Willow bark: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Willow bark yields salicylic acid, which shares renal anionic secretion pathways with cefdinir. The effect is theoretical and unlikely to be clinically important.
What this interaction means in plain words
Cefdinir and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for renal tubular organic anion transport.
What to do
No routine action is needed; avoid high-dose willow bark in renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefdinir
- Aluminum hydroxide + Cefdinir Moderate
- Cefdinir + Cholera vaccine Moderate
- Cefdinir + Famotidine Moderate
- Cefdinir + Gentamicin Moderate
- Cefdinir + Microbiota Moderate
- Cefdinir + Nizatidine Moderate
Frequently asked questions
Can I take Cefdinir with Willow bark?
MediHelp rates the interaction as minor. Cefdinir and Willow bark have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Willow bark yields salicylic acid, which shares renal anionic secretion pathways with cefdinir. The effect is theoretical and unlikely to be clinically important.
How serious is the interaction between Cefdinir and Willow bark?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; avoid high-dose willow bark in renal impairment.
What other medicines interact with Cefdinir?
MediHelp also lists interactions of Cefdinir with, for example, Aluminum hydroxide, Cholera vaccine, Famotidine. The full list is on the Cefdinir page.
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