Drug interactions
Cefoxitin + Enoxaparin
Severity: Minor
Cefoxitin and Enoxaparin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefoxitin is not known to change the anticoagulant effect of enoxaparin. They are frequently used together perioperatively. Any additional bleeding risk is theoretical.
What this interaction means in plain words
Cefoxitin and Enoxaparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cefoxitin belongs to Anti Bacterial; Enoxaparin belongs to Cardiovascular.
Why it happens
No established mechanism; only a theoretical additive hemostatic effect.
What to do
No dose change is needed; monitor for bleeding and renal function as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Cefoxitin and Enoxaparin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Cefoxitin
- Amikacin + Cefoxitin Moderate
- Aztreonam + Cefoxitin Moderate
- Bcg vaccine live + Cefoxitin Moderate
- Cefoxitin + Chloramphenicol Moderate
- Cefoxitin + Cholera vaccine Moderate
- Cefoxitin + Dexamethasone-tobramycin Moderate
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Cefoxitin with Enoxaparin?
MediHelp rates the interaction as minor. Cefoxitin and Enoxaparin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefoxitin is not known to change the anticoagulant effect of enoxaparin. They are frequently used together perioperatively. Any additional bleeding risk is theoretical.
How serious is the interaction between Cefoxitin and Enoxaparin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed; monitor for bleeding and renal function as usual.
What other medicines interact with Cefoxitin?
MediHelp also lists interactions of Cefoxitin with, for example, Amikacin, Aztreonam, Bcg vaccine live. The full list is on the Cefoxitin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
