Drug interactions
Cefpodoxime + Choline magnesium trisalicylate
Severity: Minor
Cefpodoxime and Choline magnesium trisalicylate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both are acidic compounds partly cleared by renal tubular secretion, so competition could slightly raise levels of either. The magnesium component, and anything that raises gastric pH, may reduce cefpodoxime absorption.
What this interaction means in plain words
Cefpodoxime and Choline magnesium trisalicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Renal organic anion transport competition; magnesium may reduce cefpodoxime absorption via raised gastric pH.
What to do
Take cefpodoxime at least 2 hours apart from the magnesium-containing product, and take it with food.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefpodoxime
- Aluminum hydroxide + Cefpodoxime Moderate
- Amikacin + Cefpodoxime Moderate
- Calcium carbonate + Cefpodoxime Moderate
- Calcium + Cefpodoxime Moderate
- Cefpodoxime + Cholera vaccine Moderate
- Cefpodoxime + Cimetidine Moderate
Frequently asked questions
Can I take Cefpodoxime with Choline magnesium trisalicylate?
MediHelp rates the interaction as minor. Cefpodoxime and Choline magnesium trisalicylate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both are acidic compounds partly cleared by renal tubular secretion, so competition could slightly raise levels of either. The magnesium component, and anything that raises gastric pH, may reduce cefpodoxime absorption.
How serious is the interaction between Cefpodoxime and Choline magnesium trisalicylate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take cefpodoxime at least 2 hours apart from the magnesium-containing product, and take it with food.
What other medicines interact with Cefpodoxime?
MediHelp also lists interactions of Cefpodoxime with, for example, Aluminum hydroxide, Amikacin, Calcium carbonate. The full list is on the Cefpodoxime page.
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