Drug interactions
Ceftaroline + Gentamicin
Severity: Minor
Ceftaroline and Gentamicin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ceftaroline has little intrinsic nephrotoxicity, and no clear potentiation of gentamicin toxicity is established. Renal risk mainly stems from gentamicin and the patient's condition.
What this interaction means in plain words
Ceftaroline and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive renal stress; no established mechanism.
What to do
Monitor renal function during therapy and dose both drugs according to creatinine clearance.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ceftaroline and Gentamicin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Ceftaroline with Gentamicin?
MediHelp rates the interaction as minor. Ceftaroline and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ceftaroline has little intrinsic nephrotoxicity, and no clear potentiation of gentamicin toxicity is established. Renal risk mainly stems from gentamicin and the patient's condition.
How serious is the interaction between Ceftaroline and Gentamicin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function during therapy and dose both drugs according to creatinine clearance.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
