Drug interactions
Celecoxib + Glycerol phenylbutyrate
Severity: Minor
Celecoxib and Glycerol phenylbutyrate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glycerol phenylbutyrate had no meaningful effect on celecoxib pharmacokinetics in a dedicated study, with only small reductions in exposure.
What this interaction means in plain words
Celecoxib and Glycerol phenylbutyrate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Glycerol phenylbutyrate belongs to Miscellaneous.
Why it happens
No clinically relevant mechanism; only a slight, insignificant change in celecoxib exposure.
What to do
No dose adjustment or special monitoring is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Other interactions of Glycerol phenylbutyrate
- Dexamethasone + Glycerol phenylbutyrate Major
- Glycerol phenylbutyrate + Valproic acid Major
- Cyclosporin + Glycerol phenylbutyrate Moderate
- Dexamethasone-neomycin-polymyxin + Glycerol phenylbutyrate Moderate
- Dexamethasone-tobramycin + Glycerol phenylbutyrate Moderate
- Fludrocortisone + Glycerol phenylbutyrate Moderate
Frequently asked questions
Can I take Celecoxib with Glycerol phenylbutyrate?
MediHelp rates the interaction as minor. Celecoxib and Glycerol phenylbutyrate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glycerol phenylbutyrate had no meaningful effect on celecoxib pharmacokinetics in a dedicated study, with only small reductions in exposure.
How serious is the interaction between Celecoxib and Glycerol phenylbutyrate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment or special monitoring is needed.
What other medicines interact with Celecoxib?
MediHelp also lists interactions of Celecoxib with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Celecoxib page.
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