Drug interactions
Celecoxib + Terazosin
Severity: Minor
Celecoxib and Terazosin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs such as celecoxib can blunt the antihypertensive effect of various blood pressure drugs. The effect with alpha-blockers is generally modest, but blood pressure control may be reduced with regular NSAID use.
What this interaction means in plain words
Celecoxib and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Celecoxib belongs to Musculoskeletal; Terazosin belongs to Genitourinary.
Why it happens
NSAID inhibition of renal prostaglandin synthesis causes sodium and fluid retention, opposing the antihypertensive effect.
What to do
Monitor blood pressure if celecoxib is used regularly or at higher doses. Use the lowest effective NSAID dose for the shortest duration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Celecoxib
- Celecoxib + Ketorolac Contraindicated
- Celecoxib + Ketorolac intranasal Contraindicated
- Aceclofenac + Celecoxib Major
- Acemetacin + Celecoxib Major
- Amiloride + Celecoxib Major
- Apixaban + Celecoxib Major
Frequently asked questions
Can I take Celecoxib with Terazosin?
MediHelp rates the interaction as minor. Celecoxib and Terazosin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. NSAIDs such as celecoxib can blunt the antihypertensive effect of various blood pressure drugs. The effect with alpha-blockers is generally modest, but blood pressure control may be reduced with regular NSAID use.
How serious is the interaction between Celecoxib and Terazosin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if celecoxib is used regularly or at higher doses. Use the lowest effective NSAID dose for the shortest duration.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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