Drug interactions
Certolizumab pegol + Trastuzumab
Severity: Minor
Certolizumab pegol and Trastuzumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trastuzumab is not itself strongly immunosuppressive, but it can worsen neutropenia when combined with chemotherapy. Added infection risk with certolizumab is largely theoretical and depends on concurrent chemotherapy.
What this interaction means in plain words
Certolizumab pegol and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Certolizumab pegol belongs to Musculoskeletal; Trastuzumab belongs to Oncology.
Why it happens
No established direct interaction; added infection risk reflects TNF blockade plus possible neutropenia.
What to do
Monitor neutrophil counts and signs of infection, especially with concurrent chemotherapy. No routine dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicated
- Bcg intravesical live + Certolizumab pegol Contraindicated
- Bcg vaccine live + Certolizumab pegol Contraindicated
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicated
Other interactions of Trastuzumab
Frequently asked questions
Can I take Certolizumab pegol with Trastuzumab?
MediHelp rates the interaction as minor. Certolizumab pegol and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trastuzumab is not itself strongly immunosuppressive, but it can worsen neutropenia when combined with chemotherapy. Added infection risk with certolizumab is largely theoretical and depends on concurrent chemotherapy.
How serious is the interaction between Certolizumab pegol and Trastuzumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor neutrophil counts and signs of infection, especially with concurrent chemotherapy. No routine dose adjustment is needed.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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