Drug interactions
Cevimeline + Nebivolol
Severity: Moderate
Cevimeline and Nebivolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cevimeline is a cholinergic agonist that may cause bradycardia and conduction disturbances, and beta-blockers can add to this. Bronchospasm risk may also rise in susceptible patients.
What this interaction means in plain words
Cevimeline and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cevimeline belongs to Miscellaneous; Nebivolol belongs to Cardiovascular.
Why it happens
Additive effects on cardiac conduction from muscarinic stimulation and beta-blockade.
What to do
Monitor heart rate and conduction and avoid in patients with significant conduction disease or bronchospastic disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Cevimeline
- Amitriptyline + Cevimeline Moderate
- Atenolol-chlorthalidone + Cevimeline Moderate
- Atenolol + Cevimeline Moderate
- Atropine + Cevimeline Moderate
- Betaxolol + Cevimeline Moderate
- Bethanechol + Cevimeline Moderate
Frequently asked questions
Can I take Cevimeline with Nebivolol?
MediHelp rates the interaction as moderate. Cevimeline and Nebivolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cevimeline is a cholinergic agonist that may cause bradycardia and conduction disturbances, and beta-blockers can add to this. Bronchospasm risk may also rise in susceptible patients.
How serious is the interaction between Cevimeline and Nebivolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and conduction and avoid in patients with significant conduction disease or bronchospastic disease.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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