Drug interactions
Chlordiazepoxide + Flibanserin
Severity: Moderate
Chlordiazepoxide and Flibanserin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chlordiazepoxide is a long-acting benzodiazepine, and combined use with flibanserin increases the risk of sedation, dizziness and impaired coordination. Effects may persist because of active metabolites.
What this interaction means in plain words
Chlordiazepoxide and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlordiazepoxide belongs to Central Nervous System; Flibanserin belongs to Genitourinary.
Why it happens
Additive pharmacodynamic CNS depression.
What to do
Counsel patients about sedation, avoid driving, and reduce the benzodiazepine dose or avoid the combination if drowsiness is significant.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Other interactions of Chlordiazepoxide
Frequently asked questions
Can I take Chlordiazepoxide with Flibanserin?
MediHelp rates the interaction as moderate. Chlordiazepoxide and Flibanserin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chlordiazepoxide is a long-acting benzodiazepine, and combined use with flibanserin increases the risk of sedation, dizziness and impaired coordination. Effects may persist because of active metabolites.
How serious is the interaction between Chlordiazepoxide and Flibanserin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients about sedation, avoid driving, and reduce the benzodiazepine dose or avoid the combination if drowsiness is significant.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
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