Drug interactions
Chlordiazepoxide + Lasmiditan
Severity: Moderate
Chlordiazepoxide and Lasmiditan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan commonly causes dizziness and sedation, and combining it with a benzodiazepine may intensify CNS depression. Combined use has not been formally studied.
What this interaction means in plain words
Chlordiazepoxide and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlordiazepoxide belongs to Central Nervous System; Lasmiditan belongs to Central Nervous System.
Why it happens
Additive pharmacodynamic CNS depression.
What to do
Advise patients to avoid driving for at least 8 hours after lasmiditan and to be cautious with other sedatives. Monitor for excessive drowsiness and cognitive impairment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlordiazepoxide
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Chlordiazepoxide with Lasmiditan?
MediHelp rates the interaction as moderate. Chlordiazepoxide and Lasmiditan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lasmiditan commonly causes dizziness and sedation, and combining it with a benzodiazepine may intensify CNS depression. Combined use has not been formally studied.
How serious is the interaction between Chlordiazepoxide and Lasmiditan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid driving for at least 8 hours after lasmiditan and to be cautious with other sedatives. Monitor for excessive drowsiness and cognitive impairment.
What other medicines interact with Chlordiazepoxide?
MediHelp also lists interactions of Chlordiazepoxide with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide page.
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