Drug interactions
Chlordiazepoxide + Phentermine
Severity: Minor
Chlordiazepoxide and Phentermine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Phentermine is a stimulant that may partially oppose chlordiazepoxide's sedation, but no reliable clinical interaction is documented. Effects on alertness and psychomotor performance remain unpredictable.
What this interaction means in plain words
Chlordiazepoxide and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chlordiazepoxide belongs to Central Nervous System; Phentermine belongs to Central Nervous System.
Why it happens
Opposing CNS pharmacodynamic effects; no established pharmacokinetic interaction.
What to do
No dose change is required. Advise patients that impairment may persist despite stimulant use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Chlordiazepoxide
Other interactions of Phentermine
- Isocarboxazid + Phentermine Contraindicated
- Linezolid + Phentermine Contraindicated
- Phenelzine + Phentermine Contraindicated
- Phentermine + Procarbazine Contraindicated
- Phentermine + Rasagiline Contraindicated
- Phentermine + Selegiline Contraindicated
Frequently asked questions
Can I take Chlordiazepoxide with Phentermine?
MediHelp rates the interaction as minor. Chlordiazepoxide and Phentermine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Phentermine is a stimulant that may partially oppose chlordiazepoxide's sedation, but no reliable clinical interaction is documented. Effects on alertness and psychomotor performance remain unpredictable.
How serious is the interaction between Chlordiazepoxide and Phentermine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is required. Advise patients that impairment may persist despite stimulant use.
What other medicines interact with Chlordiazepoxide?
MediHelp also lists interactions of Chlordiazepoxide with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Chlordiazepoxide page.
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