Drug interactions
Cholestyramine + Triamcinolone
Severity: Minor
Cholestyramine and Triamcinolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cholestyramine binds many drugs in the gut and can reduce absorption of orally administered corticosteroids. With injectable triamcinolone the effect is unlikely to matter. It is relevant mainly when oral steroids are taken together with the resin.
What this interaction means in plain words
Cholestyramine and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cholestyramine belongs to Cardiovascular; Triamcinolone belongs to Endocrine.
Why it happens
Binding of the corticosteroid by the anion-exchange resin in the gastrointestinal tract reduces absorption.
What to do
For oral triamcinolone, give it at least 1 hour before or 4 to 6 hours after cholestyramine. No separation is needed for injectable use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Triamcinolone
- Smallpox vaccine live + Triamcinolone Contraindicated
- Triamcinolone + Zoster vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Triamcinolone Major
- Aldesleukin + Triamcinolone Major
- Atazanavir + Triamcinolone Major
- Axicabtagene ciloleucel + Triamcinolone Major
Other interactions of Cholestyramine
Frequently asked questions
Can I take Cholestyramine with Triamcinolone?
MediHelp rates the interaction as minor. Cholestyramine and Triamcinolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cholestyramine binds many drugs in the gut and can reduce absorption of orally administered corticosteroids. With injectable triamcinolone the effect is unlikely to matter. It is relevant mainly when oral steroids are taken together with the resin.
How serious is the interaction between Cholestyramine and Triamcinolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: For oral triamcinolone, give it at least 1 hour before or 4 to 6 hours after cholestyramine. No separation is needed for injectable use.
What other medicines interact with Triamcinolone?
MediHelp also lists interactions of Triamcinolone with, for example, Smallpox vaccine live, Zoster vaccine live, Adenovirus types 4 and 7 live. The full list is on the Triamcinolone page.
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