Drug interactions
Cholestyramine + Vitamin a
Severity: Minor
Cholestyramine and Vitamin a: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cholestyramine can reduce absorption of fat-soluble vitamins, including vitamin A, particularly with long-term use or poor dietary intake. Deficiency may develop over time.
What this interaction means in plain words
Cholestyramine and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cholestyramine belongs to Cardiovascular; Vitamin a belongs to Gastrointestinal Tract.
Why it happens
Cholestyramine binds bile acids and impairs micelle formation, reducing absorption of fat-soluble vitamins.
What to do
Separate vitamin A from cholestyramine by at least 4 hours after, or 1 hour before. Consider monitoring vitamin A status in long-term therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cholestyramine
Other interactions of Vitamin a
- Acitretin + Vitamin a Major
- Etretinate + Vitamin a Major
- Isotretinoin + Vitamin a Major
- Palovarotene + Vitamin a Major
- Bexarotene + Vitamin a Moderate
- Minocycline + Vitamin a Moderate
Frequently asked questions
Can I take Cholestyramine with Vitamin a?
MediHelp rates the interaction as minor. Cholestyramine and Vitamin a have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cholestyramine can reduce absorption of fat-soluble vitamins, including vitamin A, particularly with long-term use or poor dietary intake. Deficiency may develop over time.
How serious is the interaction between Cholestyramine and Vitamin a?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate vitamin A from cholestyramine by at least 4 hours after, or 1 hour before. Consider monitoring vitamin A status in long-term therapy.
What other medicines interact with Cholestyramine?
MediHelp also lists interactions of Cholestyramine with, for example, Cholic acid, Deferasirox, Leflunomide. The full list is on the Cholestyramine page.
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