Drug interactions
Choline magnesium trisalicylate + Esmolol
Severity: Minor
Choline magnesium trisalicylate and Esmolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salicylates at anti-inflammatory doses may blunt the antihypertensive effect of beta-blockers. Esmolol is short-acting, so the effect is usually modest. Trisalicylate has less effect on platelets and prostaglandins than other NSAIDs but some effect is possible.
What this interaction means in plain words
Choline magnesium trisalicylate and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Reduced prostaglandin synthesis may cause sodium and fluid retention, opposing beta-blocker blood pressure lowering.
What to do
Monitor blood pressure and heart rate response to esmolol and titrate accordingly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Esmolol
- Acebutolol + Esmolol Major
- Amifostine + Esmolol Major
- Amiodarone + Esmolol Major
- Celiprolol + Esmolol Major
- Diltiazem + Esmolol Major
- Epinephrine racemic + Esmolol Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Esmolol?
MediHelp rates the interaction as minor. Choline magnesium trisalicylate and Esmolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Salicylates at anti-inflammatory doses may blunt the antihypertensive effect of beta-blockers. Esmolol is short-acting, so the effect is usually modest. Trisalicylate has less effect on platelets and prostaglandins than other NSAIDs but some effect is possible.
How serious is the interaction between Choline magnesium trisalicylate and Esmolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate response to esmolol and titrate accordingly.
What other medicines interact with Esmolol?
MediHelp also lists interactions of Esmolol with, for example, Acebutolol, Amifostine, Amiodarone. The full list is on the Esmolol page.
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