Drug interactions
Choline magnesium trisalicylate + Furosemide
Severity: Moderate
Choline magnesium trisalicylate and Furosemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salicylates at anti-inflammatory doses can reduce the diuretic response to furosemide and compete for renal tubular secretion. Renal function may worsen in volume-depleted patients, and salicylate toxicity is possible with reduced clearance.
What this interaction means in plain words
Choline magnesium trisalicylate and Furosemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Prostaglandin inhibition and competition for organic anion tubular secretion.
What to do
Monitor diuretic response, renal function and salicylate symptoms or levels, and adjust furosemide dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Furosemide?
MediHelp rates the interaction as moderate. Choline magnesium trisalicylate and Furosemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Salicylates at anti-inflammatory doses can reduce the diuretic response to furosemide and compete for renal tubular secretion. Renal function may worsen in volume-depleted patients, and salicylate toxicity is possible with reduced clearance.
How serious is the interaction between Choline magnesium trisalicylate and Furosemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor diuretic response, renal function and salicylate symptoms or levels, and adjust furosemide dose as needed.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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