Drug reference
furosemide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Diuretics)
Mechanism of action
Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride
Common side effects
- Anorexia
- Anemia
- Hyperuricemia
- Hypokalemia
- Diarrhea
Contraindications
- Documented hypersensitivity to furosemide or sulfonamides Anuria
Known interactions (14)
- Digoxin + furosemide Major
- furosemide + gentamicin Major
- Amlodipine + furosemide Moderate
- aspirin + furosemide Moderate
- Azithromycin + furosemide Moderate
- furosemide + Glimepiride Moderate
- furosemide + insulin Moderate
- furosemide + lansoprazole Moderate
- furosemide + lisinopril Moderate
- furosemide + metformin Moderate
- furosemide + methyldopa Moderate
- furosemide + probenecid Moderate
- furosemide + spironolactone Moderate
- furosemide + Vancomycin Moderate
Related conditions
Frequently asked questions
What drug class is furosemide?
furosemide belongs to: Cardiovascular.
How does furosemide work?
Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride
What are the common side effects of furosemide?
Anorexia, Anemia, Hyperuricemia, Hypokalemia, Diarrhea
Which drugs interact with furosemide?
Digoxin, gentamicin, Amlodipine, aspirin, Azithromycin, Glimepiride, insulin, lansoprazole, lisinopril, metformin, methyldopa, probenecid, spironolactone, Vancomycin
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