Drug interactions
Choline magnesium trisalicylate + Gentamicin
Severity: Minor
Choline magnesium trisalicylate and Gentamicin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Choline magnesium trisalicylate has less effect on renal prostaglandins than most NSAIDs, so the interaction with gentamicin is limited. High doses or dehydration could still contribute to renal stress and raise gentamicin levels.
What this interaction means in plain words
Choline magnesium trisalicylate and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modest reduction in renal perfusion from salicylate; weaker prostaglandin inhibition than other NSAIDs.
What to do
Monitor renal function and gentamicin levels if high-dose salicylate is used, and ensure adequate hydration.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gentamicin
- Cidofovir + Gentamicin Contraindicated
- Adefovir + Gentamicin Major
- Amikacin + Gentamicin Major
- Amlodipine-hydrochlorothiazide-valsartan + Gentamicin Major
- Amphotericin b deoxycholate + Gentamicin Major
- Amphotericin b + Gentamicin Major
Frequently asked questions
Can I take Choline magnesium trisalicylate with Gentamicin?
MediHelp rates the interaction as minor. Choline magnesium trisalicylate and Gentamicin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Choline magnesium trisalicylate has less effect on renal prostaglandins than most NSAIDs, so the interaction with gentamicin is limited. High doses or dehydration could still contribute to renal stress and raise gentamicin levels.
How serious is the interaction between Choline magnesium trisalicylate and Gentamicin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and gentamicin levels if high-dose salicylate is used, and ensure adequate hydration.
What other medicines interact with Gentamicin?
MediHelp also lists interactions of Gentamicin with, for example, Cidofovir, Adefovir, Amikacin. The full list is on the Gentamicin page.
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