Drug interactions
Chromium + Gliclazide
Severity: Minor
Chromium and Gliclazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chromium supplements may modestly improve insulin sensitivity and could add to the glucose-lowering effect of gliclazide. Clinical evidence is limited and inconsistent.
What this interaction means in plain words
Chromium and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Chromium belongs to Gastrointestinal Tract; Gliclazide belongs to Endocrine.
Why it happens
Possible enhancement of insulin action by chromium, additive to sulfonylurea effect.
What to do
Monitor blood glucose when chromium supplements are started and reduce gliclazide if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Gliclazide
Other interactions of Chromium
- Chromium + Omadacycline Moderate
- Chromium + Sarecycline Moderate
- Acarbose + Chromium Minor
- Acetylsalicylic acid + Chromium Minor
- Alogliptin-metformin + Chromium Minor
- Alogliptin-pioglitazone + Chromium Minor
Frequently asked questions
Can I take Chromium with Gliclazide?
MediHelp rates the interaction as minor. Chromium and Gliclazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chromium supplements may modestly improve insulin sensitivity and could add to the glucose-lowering effect of gliclazide. Clinical evidence is limited and inconsistent.
How serious is the interaction between Chromium and Gliclazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when chromium supplements are started and reduce gliclazide if hypoglycemia occurs.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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